Urinary tract infection
Lomefloxacin oral preparation is indicated for the treatment of:
-
- Uncomplicated urinary tract infections.
- Complicated including recurrent and pyelonephritis, urinary tract infections.
- Acute exacerbation of chronic bronchitis.
- Skin and skin structure infections.
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Lomefloxacin oral preparation is indicated for the treatment of:
- Uncomplicated urinary tract infections.
- Complicated including recurrent and pyelonephritis, urinary tract infections.
- Acute exacerbation of chronic bronchitis.
- Skin and skin structure infections.
Prevention/Prophylaxis: Lomefloxacin is indicated preperatively to prevent postoperative urinary tract infections in patients undergoing transurethral surgical procedures.
Cross-resistance has only been reported with other quinolones, but not with any other group of antibiotics. No clinical studies are available about the efficacy in cases of infections with chlamydia.
Typhoid fever: 400 mg once daily or 200 mg b.i.d 10-14 days.
UTI infections:
- Uncomplicated: 400 mg once daily or 200 mg b.i.d 3 days.
- Complicated: 400 mg once daily or 200 mg b.i.d 10-14 days.
Bacterial Diarrhea: 400 mg once daily or 200 mg b.i.d 5-7 days.
Acute exacerbation of chronic bronchitis: 400 mg once daily 7-10 days.
Skin and skin structure infections: 400 mg once daily 10-14 days.
Prophylaxis of UTI following surgery: 400 mg Single dose 2-6 hours prior to transurethral surgery.
Nursing mothers: It is not known whether lomefloxacin is excreted in human milk. However, it is known that other drugs of this class are excreted in human milk and that lomefloxacin is excreted in the milk of lactating rats. Because of the potential for serious adverse reactions from lomefloxacin in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Geriatric use: Of the total number of subjects in clinical studies of lomefloxacin, 25% were ≥65 years and 9% were ≥ 75 years. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.