Bilosen

Bilosen

Generic name: Bilastine

20 mg

Manufactured by: Novatek Pharmaceuticals Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

Indication

Urticaria

Bilastine is indicated for symptomatic treatment of allergic rhino-conjunctivitis (seasonal and perennial) and urticaria.

Pharmacology

Bilastine is a non-sedating, long-acting histamine antagonist with selective peripheral H 1 receptor antagonist affinity and no affinity for muscarinic receptors. Bilastine inhibits histamine-induced wheal and flare skin reactions for 24 hours following single doses.

Dosage & Administration

Interaction

Concomitant intake of Bilastine and Ketoconazole or Erythromycin or Diltiazem increased C max of Bilastine. The psychomotor performance after concomitant intake of alcohol and Bilastine was similar to that observed after intake of alcohol and placebo. Concomitant intake of Bilastine and Lorazepam 3 mg for 8 days did not potentiate the depressant CNS effects of Lorazepam.

Side Effects

The most commonly reported side effects in clinical trial are headache, dizziness, somnolence and fatigue. These adverse events occurred with a comparable frequency in patients receiving placebo.

Pregnancy & Lactation

There are no or limited amount of data from the use of Bilastine in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity, parturition or postnatal development. As a precautionary measure, it is preferable to avoid the use of Bilastine during pregnancy. The excretion of Bilastine in milk has not been studied in humans. A decision must be made taking into account the benefit of breast-feeding for the child and the benefit of Bilastine therapy for the mother.

Precautions & Warnings

Co-administration of Bilastine and P-glycoprotein inhibitors (e.g. Ketoconazole, Erythromycin, Cyclosporine, Ritonavir or Diltiazem) should be avoided in patients with moderate or severe renal impairment.

Use in Special Populations

Efficacy and safety of Bilastine in children under 2 years of age have not been established and there is little clinical experience in children aged 2 to 5 years, therefore Bilastine should not be used in these age groups.

Therapeutic Class

Non-sedating antihistamines

Overdose Effects

In clinical trials, after administration of Bilastine at doses 10 to 11 times the therapeutic dose (220 mg as single dose; or 200 mg/day for 7 days) frequency of treatment-emergent adverse events was two times higher than with placebo. The adverse reactions most frequently reported were dizziness, headache and nausea. No serious adverse events and no significant prolongation in the QTc interval were reported.

Storage Conditions

Keep below 30°C temperature, protected from light and moisture. Keep out of reach of children.

Alternative Brand Names

20 mg

Navana Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Navana Pharmaceuticals Ltd.

60 ml bottle: ৳ 120.00

20 mg

Pacific Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Opsonin Pharma Ltd.

Unit Price: ৳ 15.00 (3 x 14: ৳ 630.00)

Strip Price: ৳ 210.00

12.5 mg/5 ml

Opsonin Pharma Ltd.

60 ml bottle: ৳ 140.00

Dispersible Tablet

10 mg

Opsonin Pharma Ltd.

Unit Price: ৳ 15.00 (3 x 14: ৳ 630.00)

Strip Price: ৳ 210.00

20 mg

Sharif Pharmaceuticals Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

12.5 mg/5 ml

Sharif Pharmaceuticals Ltd.

50 ml bottle: ৳ 100.00

20 mg

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

20 mg

Ibn Sina Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Ibn Sina Pharmaceuticals Ltd.

60 ml bottle: ৳ 140.00

10 mg

Ibn Sina Pharmaceuticals Ltd.

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)

Strip Price: ৳ 120.00

20 mg

ACME Laboratories Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

ACME Laboratories Ltd.

50 ml bottle: ৳ 100.00

Dispersible Tablet

10 mg

ACME Laboratories Ltd.

Price Unavailable

20 mg

Beacon Pharmaceuticals PLC

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)

12.5 mg/5 ml

Beacon Pharmaceuticals PLC

60 ml bottle: ৳ 140.00

20 mg

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Ziska Pharmaceuticals Ltd.

50 ml bottle: ৳ 100.00

Dispersible Tablet

10 mg

Ziska Pharmaceuticals Ltd.

Unit Price: ৳ 10.00, (30's pack: ৳ 300.00)

Dispersible Tablet

10 mg

Ziska Pharmaceuticals Ltd.

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)

Strip Price: ৳ 100.00

20 mg

Team Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)

12.5 mg/5 ml

Team Pharmaceuticals Ltd.

60 ml bottle: ৳ 130.00

20 mg

Popular Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Popular Pharmaceuticals Ltd.

60 ml bottle: ৳ 120.00

Dispersible Tablet

10 mg

Popular Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Apex Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)

12.5 mg/5 ml

One Pharma Ltd.

60 ml bottle: ৳ 120.00

20 mg

One Pharma Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

20 mg

Albion Laboratories Limited

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)

Strip Price: ৳ 180.00

20 mg

NIPRO JMI Pharma Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

NIPRO JMI Pharma Ltd.

40 ml bottle: ৳ 90.00

20 mg

Square Pharmaceuticals PLC

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)

Dispersible Tablet

10 mg

Square Pharmaceuticals PLC

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Beximco Pharmaceuticals Ltd.

60 ml bottle: ৳ 140.00

20 mg

Beximco Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

Dispersible Tablet

10 mg

Beximco Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Eskayef Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)
Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Eskayef Pharmaceuticals Ltd.

30 ml bottle: ৳ 75.00

Dispersible Tablet

10 mg

Eskayef Pharmaceuticals Ltd.

Unit Price: ৳ 13.00, (30's pack: ৳ 390.00)

20 mg

Everest Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (20's pack: ৳ 300.00)

12.5 mg/5 ml

Everest Pharmaceuticals Ltd.

60 ml bottle: ৳ 140.00

20 mg

Orion Pharma Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

Dispersible Tablet

10 mg

General Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

General Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Somatec Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

Dispersible Tablet

10 mg

Somatec Pharmaceuticals Ltd.

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)

Strip Price: ৳ 120.00

20 mg

C2C Pharma Ltd.

Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)

Strip Price: ৳ 100.00

Alternate Brands

20 mg

Euro Pharma Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

20 mg

Nuvista Pharma Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Delta Pharma Ltd.

Unit Price: ৳ 10.00, (30's pack: ৳ 300.00)

20 mg

Radiant Pharmaceuticals Ltd.

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)

Strip Price: ৳ 150.00

20 mg

Drug International Ltd.

Unit Price: ৳ 15.00, (28's pack: ৳ 420.00)

20 mg

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

20 mg

Pharmasia Limited

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Pharmasia Limited

30 ml bottle: ৳ 75.00

20 mg

Incepta Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)

12.5 mg/5 ml

Incepta Pharmaceuticals Ltd.

60 ml bottle: ৳ 140.00

20 mg

Healthcare Pharmaceuticals Ltd.

Unit Price: ৳ 15.00, (30's pack: ৳ 450.00)