Generic name: Cefixime Trihydrate
400 mg
Manufactured by: Incepta Pharmaceuticals Ltd.
Unit Price: ৳ 50.00 (2 x 4: ৳ 400.00)
Strip Price: ৳ 200.00
Urethritis
Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:
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- Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis.
- Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes.
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Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:
- Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis.
- Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes.
- Pharyngitis and tonsillitis caused by Streptococcus pyogenes.
- Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae.
- Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.
Cefixime is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It kills bacteria by interfering in the synthesis of bacterial cell wall. It is highly stable in the presence of Beta-lactamase enzyme. As a result, many organisms resistant to penicillins and some cephalsporins due to the presence of beta-lactamases, may be susceptible to Cefixime. Absorption of it is about 40% to 50% whether administered with or without food.
Carbamazepine: Concomitant use elevates the carbamazepine level. Warfarin and other anticoagulants: Concomitant use increases prothrombin time.
The drug is generally well tolerated. The most frequent side effects are diarrhoea and stool changes; that have been more commonly associated with higher doses. Other side effects are nausea, abdominal pain, dyspepsia, vomiting, flatulence, headache and dizziness. Allergies in the form of rash, pruritus, urticaria, drug fever and arthralgia have been reported. These reactions usually subsided upon dicontinuation of therapy.
There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It is not known that Cefixime is excreted in human milk. So, caution should be exercised when Cefixime is administered to a nursing woman.
The drug should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. The drug should be given with caution in patients with marked impaired renal function as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml/min), in that case a dose of 200 mg once daily should not be exceeded.
Third generation Cephalosporins
Gastric Lavage may be indicated; otherwise, no specific antidote exists. Cefixime is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis. Adverse reactions in small numbers of healthy adult volunteers receiving single doses up to 2 g of Cefixime did not differ from the profile seen in patients treated at the recommended doses.
Keep below 30ºC temperature, protected from light & moisture. Keep out of the reach of children.
Alternative Brand Names
100 mg/5 ml
37.5 ml bottle: ৳ 130.00, 50 ml bottle: ৳ 160.00
200 mg
Unit Price: ৳ 35.00 (2 x 7: ৳ 490.00)
Strip Price: ৳ 245.00
400 mg
Unit Price: ৳ 50.00 (2 x 7: ৳ 700.00)
Strip Price: ৳ 350.00
100 mg/5 ml
37.5 ml bottle: ৳ 130.00, 50 ml bottle: ৳ 210.00
200 mg
Unit Price: ৳ 30.00, (12's pack: ৳ 360.00)
Unit Price: ৳ 30.00, (14's pack: ৳ 420.00)
Unit Price: ৳ 30.00, (14's pack: ৳ 420.00)
100 mg/5 ml
30 ml bottle: ৳ 120.37, 50 ml bottle: ৳ 175.00
200 mg
Unit Price: ৳ 35.00, (12's pack: ৳ 420.00)
400 mg
Unit Price: ৳ 52.50, (8's pack: ৳ 420.00)
100 mg/5 ml
30 ml bottle: ৳ 135.40, 50 ml bottle: ৳ 210.63, 75 ml bottle: ৳ 250.00
100 mg/5 ml
37.5 ml bottle: ৳ 130.00, 50 ml bottle: ৳ 160.00
100 mg/5 ml
30 ml bottle: ৳ 130.39, 50 ml bottle: ৳ 210.63, 75 ml bottle: ৳ 241.62
400 mg
Unit Price: ৳ 55.00 (2 x 6: ৳ 660.00)
Strip Price: ৳ 330.00
200 mg
Unit Price: ৳ 35.00 (2 x 6: ৳ 420.00)
Strip Price: ৳ 210.00
400 mg
Unit Price: ৳ 50.00 (1 x 7: ৳ 350.00)
Strip Price: ৳ 350.00
200 mg
Unit Price: ৳ 30.00 (2 x 7: ৳ 420.00)
Strip Price: ৳ 210.00
400 mg
Unit Price: ৳ 55.00, (20's pack: ৳ 1, 100.00)
100 mg/5 ml
30 ml bottle: ৳ 130.00, 40 ml bottle: ৳ 180.00, 50 ml bottle: ৳ 210.00, 75 ml bottle: ৳ 240.00
400 mg
Unit Price: ৳ 65.00 (2 x 7: ৳ 910.00)
Strip Price: ৳ 455.00