Generic name: Gatifloxacin (Oral)
400 mg
Manufactured by:
Unit Price: ৳ 10.04, (18's pack: ৳ 180.72)
Urinary tract infection
Gatifloxacin is indicated in the following infections:
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- Acute bacterial exacerbation of chronic bronchitis due to Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Staphylococcus aureus.
- Acute sinusitis due to Streptococcus pneumoniae or Haemophilus influenzae.
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Gatifloxacin is indicated in the following infections:
- Acute bacterial exacerbation of chronic bronchitis due to Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Staphylococcus aureus.
- Acute sinusitis due to Streptococcus pneumoniae or Haemophilus influenzae.
- Community-acquired pneumonia due to Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Staphylococcus aureus, Mycoplasma pneumoniae, Chlamydia pneumoniae, or Legionella pneumophila.
- Uncomplicated skin and skin structure infections (i.e., simple abscesses, furuncles, folliculitis, wound infections, and cellulitis) due to Staphylococcus aureus or Streptococcus pyogenes.
- Uncomplicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis.
- Complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis.
- Pyelonephritis due to Escherichia coli.
- Uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae.
- Acute, uncomplicated rectal infections in women due to Neisseria gonorrhoeae.
Gatifloxacin is a fluoroquinolone antibacterial which acts by inhibiting DNA synthesis in susceptible organisms via inhibition of both DNA gyrase (essential for bacterial reproduction) and topoisomerase IV (essential during bacterial cell division).
Gatifloxacin is generally well tolerated. The most common side effects that can occur while taking this drug are usually mild and include nausea, vomiting, stomach pain, diarrhea, dizziness,and headache .
Pregnancy: Gatifloxacin should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.
Lactation: It is not known whether Gatifloxacin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when gatifloxacin is administered to a nursing woman.
Gatifloxacin should be administered with caution in the presence of renal insufficiency.
Renal Impaired patient:
- Creatinine Clearance 40 mL/min: 400 mg every day.
- Creatinine Clearance < 40 mL/min: 400 mg 200 mg every day.
Dialysis patients:
- Hemodialysis: 400 mg 200 mg every day.
- Continuous peritoneal dialysis: 400 mg 200 mg every day.
Pediatric use: The safety and effectiveness of Gatifloxacinacin in pediatric populations (<18 years of age) have not been established.
4-Quinolone preparations
Gatifloxacin exhibits a low potential for acute toxicity in animal studies. In the event of acute oral overdose, the stomach should be emptied by inducing vomiting or by gastric lavage. The patient should be carefully observed (including ECG monitoring) and given symptomatic and supportive treatment. Adequate hydration should be maintained.
