Indus

50 mg

Manufactured by: Eskayef Pharmaceuticals Ltd.

Unit Price: ৳ 5.50 (5 x 10: ৳ 275.00)

Strip Price: ৳ 55.00

Indication

Itopride tablet is indicated in gastrointestinal symptoms in chronic gastritis (feeling of an enlarged abdomen, upper abdominal pain, anorexia, heartburn, nausea and vomiting).

Pharmacology

Itopride Hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase inhibitor. It increases acetylcholine concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Higher acetylcholine increases Gl peristalsis, increases the lower esophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.

Dosage & Administration

Interaction

Itopride Hydrochloride should be administered with care when co-administered with the following drugs:

Anticholinergic Drugs, Tiquizium bromide, Scopolamine butyl bromide, Timepidium bromide, etc.

Sign: There is a possibility of reducing the activity of Itopride Hydrochloride which activates gastrointestinal motility (cholinergic action).
Mechanism & risc factor: Gastrointestinal motility inhibitory action of Anticholinergic pharmacologically decreases the activity of the drug.

Side Effects

Pregnancy & Lactation

Important Precautions: Itopride Hydrochloride should be used with caution since it enhances the action of acetylcholine. This drug should not be consumed continuously for an extended period when no improvement of gastrointestinal symptoms is observed.

Precautions concerning Use: When granting agent: For drugs packaged in a press-through package (PTP), instruct the patient to remove the drug from the package prior to ingestion. (It has been reported that, by accidental ingestion of the PTP sheet, the hard and sharp corners may puncture the esophageal mucosa, or even lead to perforation resulting in serious complications such as mediastinal sinusitis.)

Precautions & Warnings

Use in Special Populations

Therapeutic Class

Osmotic purgatives

Overdose Effects

In case of excessive overdose, the usual measures of gastric lavage and symptomatic therapy should be applied.

Storage Conditions

Store below 30°C, in a cool and dry place. Keep away from light. Keep all the medicine out of the reach of children.

Indus

Alternative Brand Names