Lymeclin

Lymecycline is a tetracycline derivative which blocks the access of bacterial aminoacyl-tRNA to the mRNA-ribosome complex by binding to the 30S ribosome subunit, preventing the addition of amino acids to the growing peptide chain in protein synthesis

Decreased absorption with Ca, Al, Mg, bismuth and zinc salts, antacids, bismuth containing ulcer-healing drugs, Fe preparations and quinapril. Increased effects of anticoagulants. Decreased plasma levels with barbiturates, phenytoin or carbamazepine.

Lymecycline capsules may also cause the following
side effects.

Common (occur in less than 1 in 10 patients):

• Feeling sick (nausea)
• Abdominal pain
• Diarrhoea
• Headache

Unknown (frequency cannot be estimated from
available information):

• Eyesight disturbances
• Dizziness
• Being sick (vomiting)
• Yellowing of eyes or skin (jaundice)
• Increased sensitivity of the skin to sunlight (real or artificial)
• Increased pressure in the brain
• Changes in type or number of certain blood cells
• Pain in the upper part of the abdomen
• Changes in some blood tests (liver function tests)
• Fever
• Itchiness, skin rash, or hives
• Inflammation of the intestine

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Lymecycline capsules must not to be taken if you are pregnant or breast feeding. Use of medicines such as Lymecycline capsules may affect the proper growth of developing teeth or bones, and lead to permanent tooth discolouration.

Patient with myasthenia gravis. May exacerbate SLE. Hepatic impairment.

Tetracycline group of drugs

Store below 25° C. Protect from light.