Magnesium Oxide is indicated for the treatment of following condition:
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- Relieving the symptoms of magnesium defciency
- Cardiovascular system: Rapid heartbeat, heart rate irregularity, heart attack, angina pectoris (chest pain caused by narrowing / obstruction of heart-feeding vessels), mild severe hypertension
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Magnesium Oxide is indicated for the treatment of following condition:
- Relieving the symptoms of magnesium defciency
- Cardiovascular system: Rapid heartbeat, heart rate irregularity, heart attack, angina pectoris (chest pain caused by narrowing / obstruction of heart-feeding vessels), mild severe hypertension
- Nervous system and muscles: Sudden and excessive contractions (tetania) in the muscles, muscle cramp, gastrointestinal cramps, increased stimulability of muscles and nerves, calf cramps, cramp conditions in newborn and young children and stress
- Gynecological diseases, birth and pregnancy: Pre-term contraction, cervical insufciency, premature membrane rupture, contractions during pregnancy (eclampsia [Disease with seizures, blood pressure increase, protein in the urine, water retention in body during pregnancy]/preeclampsia [Disease with blood pressure increase, protein in the urine, water retention in body during pregnancy]), tocolysis requiring the use of beta mimetic (interruption of the uterine contractions), dysmenorrhea.
- Orthopedics: Calcifcation and ossifcation
- Prevention of kidney stone formation (prevention of recurrence of calcium oxalate urolithiasis)
- Diabetes treatment and migraine (a kind of headache)
Pharmacokinetics: Absorption of a micronutrient as Mg is affected by other nutrients and reaches an estimated 30–50% of dietary Mg intake at basal conditions, while the absorption fraction declines with age and raising Mg intake. The drug absorption depends on both the kind of Mg salt and other food elements that may either augment or abate it. The distribution of Mg is mainly intracellular, <1% circulates in the blood (both extracellularly and intracellularly), and total serum Mg comprises three states with roughly 60% ionized, 33% protein-bound and 7% anion complexed. Elimination of Mg is handled by renal filtration with 25% being reabsorbed in the proximal convoluted tubule and further 50–60% is reabsorbed in the loop of Henle. Around 70–80% of plasma Mg undergoes glomerular filtration, but merely 3% is eventually excreted in the urine.