Dinoprostone is indicated to helps in the induction of labor, and widens the cervix for easy delivery. It is also used to initiate an abortion at about 12 to 20 weeks of pregnancy and also indicated to help clean out the vagina after a miscarriage.
With Medicine: It is not advised to use Dinoprostone concurrently with oxytocic medications, since it may increase their action. For the successive use of oxytocin after removing the Dinoprostone vaginal insert, a dosage interval of at least 30 minutes is advised. There are no known interactions between other drugs.
With Food and Others: Dinoprostone is known to interact with alcohol. So, do not consume alcohol while using Dinoprostone.
Uncommon: Nausea, Vomiting, Fever, Abdominal Pain, Diarrhea.
Rare: Disseminated Intravascular Coagulation, Uterine Rupture, Anaphylactic Reaction.
Dinoprostone classified in FDA pregnancy category C. It is not recommended during pregnancy, labor or delivery and in mothers who are breast feeding.
Caution should be exercised in administration of Dinoprostone Gel in patients with: Hypertonus, Sustained Uterine Contractility or Fetal Distress, Hypertonic Uterine Contractility or Tetanic Uterine Contractions, Asthma, Glaucoma, Heart Diseases, Depression.
Store in a cool (not above 8°C) and dry place, away from light & moisture. Keep all medicines out of reach of children.