Wormex
Generic name: Albendazole
400 mg
Manufactured by: Syntho Laboratories Ltd.
Unit Price: ৳ 3.50, (26's pack: ৳ 91.00)
Worm infections
Albendazole is indicated in single and mixed infestations of-
- Hookworm (Ancylostoma, Necator)
- Roundworm (Ascaris)
- Threadworm (Enterobius)
- Whipworm (Trichuris)
- Strongyloides
- Tapeworm
- Opisthorchi
- Hydatid.
Albendazole is a broad spectrum anthelmintic. Albendazole exhibits vermicidal, ovicidal and larvicidal activities. The drug is thought to exert its anthelmintic effect by blocking glucose uptake in the susceptible helminths, thereby depleting the energy level until it becomes inadequate for survival. Immobilization is followed by the parasite. These events may be a consequence of the binding and subsequent inhibition of parasite tubulin polymerization by Albendazole and its metabolites, although the drug also binds to human tubulin. Albendazole is extensively metabolized, probably in the liver. Albendazole is poorly absorbed from the gastrointestinal tract but rapidly undergoes extensive first-pass metabolism. The principal metabolite albendazole sulphoxide has anthelmintic activity and a plasma half-life of about 8.5 hrs. It is excreted in the urine together with other metabolites.
No interaction involving Albendazole, either pharmacodynamic or pharmacokinetic, has been reported.
Gastrointestinal disturbances, headache, dizziness, changes in liver enzymes, rarely reversible alopecia; rash, fever, blood disorders including leucopenia and pancytopenia reported; allergic shock if cyst leakage; convulsion and meningism in cerebral disease.
US FDA Pregnancy category of Albendazole is C. So, Albendazole should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
Blood counts and liver function tests before treatment and twice during each cycle; breastfeeding; exclude pregnancy before starting treatment. Albendazole should only be used in the treatment of Echinococcosis if there is constant medical supervision with regular monitoring of serum-transaminase concentrations and of leucocyte and platelet counts
Anthelmintic
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Alternative Brand Names
400 mg
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
400 mg
Unit Price: ৳ 5.00, (24's pack: ৳ 120.00)
Unit Price: ৳ 5.00, (60's pack: ৳ 300.00)
400 mg
Unit Price: ৳ 4.00, (50's pack: ৳ 200.00)
Unit Price: ৳ 4.00, (100's pack: ৳ 400.00)
400 mg
Unit Price: ৳ 5.00 (20 x 3: ৳ 300.00)
Strip Price: ৳ 15.00